FOX-04-DRI
FOXO4-DRI is a peptide that targets senescent cells, helping to promote cellular health and reduce the effects of aging. It’s studied for its potential to eliminate damaged cells that contribute to aging and disease progression.
Overview
What is FOX-04-DRI?
FOXO4-DRI is a synthetic peptide designed to disrupt the interaction between the FOXO4 protein and p53, a protein responsible for regulating cell death. By selectively inducing apoptosis in senescent cells (old, damaged cells that no longer divide), FOXO4-DRI has the potential to slow down aging and promote tissue regeneration. It’s being researched for its role in anti-aging therapies and the treatment of age-related diseases.
How Does FOX-04-DRI Work?
FOXO4-DRI works by disrupting the interaction between the FOXO4 protein and p53, selectively inducing apoptosis in senescent cells. By targeting these non-dividing, damaged cells, it helps reduce inflammation and promotes healthier tissue regeneration, contributing to anti-aging effects.
Benefits
Senescent Cell Clearance
FOXO4-DRI promotes the elimination of senescent cells, which accumulate with age and contribute to chronic inflammation and tissue degradation.
Anti-Aging Properties
By clearing damaged cells, FOXO4-DRI may reduce the negative effects of aging, potentially improving tissue regeneration and overall health.
Improved Cellular Health
FOXO4-DRI supports healthier cellular function by removing cells that no longer divide, improving tissue function and reducing age-related damage.
In-Depth
The Science Behind FOXO4-DRI
FOXO4-DRI is a senolytic peptide that specifically targets senescent cells by disrupting the interaction between FOXO4 and p53, which normally prevents the activation of apoptosis in these cells. Senescent cells accumulate over time and contribute to aging and chronic diseases by releasing pro-inflammatory signals. FOXO4-DRI induces cell death in these harmful cells without affecting healthy cells, thus promoting tissue regeneration and reducing inflammation. This targeted approach makes FOXO4-DRI a promising candidate for anti-aging therapies and the treatment of diseases linked to cellular senescence.
